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Leading Esketamine Therapy Center in Euless, TX

Mid Cities Psychiatry has been at the forefront of bringing life-changing treatment options for people with mental health conditions. To enhance our clinical excellence further, we bring to you the best Esketamine therapy in Euless.

Esketamine therapy, which is primarily administered as a nasal spray, is an FDA-approved treatment for adults with treatment-resistant depression (TRD) and major depressive disorder (MDD) in adults with acute suicidal thoughts or actions. Esketamine for depression is used in conjunction with a conventional oral antidepressant or in cases that haven’t improved with oral medications and psychotherapies.

Esketamine Treatment: The Evolution of Healing

While standard depression medications often take weeks or months to show effects, Esketamine treatment shifts the traditional paradigm in psychiatric intervention. Mid Cities’ esketamine therapy provides relief within hours and days. It works by blocking the brain receptors affecting mood. By acting on these receptors, esketamine improves the symptoms of severe or treatment-resistant depression that do not go away with standard antidepressants.

Rapid Relief in Symptoms: Esketamine Treatment for Depression shows quick improvement within hours or days.

FDA-approved: It is the first and only FDA-approved Esketamine nasal spray.
Result-Oriented Outcome: Esketamine therapy brings a high success rate in symptom relief where other options fail.
Easy, Safe, and Non-Invasive: Comfortable and painless, esketamine nasal spray becomes a superior choice for treatment-resistant depression.

Esketamine for Depression: The Science Behind Rapid Relief

Unlike standard antidepressants that primarily affect serotonin, Esketamine treatment works on the brain’s glutamate system, specifically targeting NMDA receptors. By modulating glutamate activity, Esketamine therapy helps:

Restore synaptic connections in areas of the brain involved in mood regulation
Improve communication between brain cells
Promote neuroplasticity (the brain’s ability to adapt and form new pathways)

Because of this unique mechanism, some patients may experience improvement more rapidly than with conventional antidepressants.

Administration of Esketamine Nasal Spray

Esketamine is administered as a nasal spray in our clinic under direct medical supervision.

Treatment typically follows this schedule:

Induction phase: Twice weekly for the first 4 weeks
Maintenance phase: Once weekly or once every two weeks, depending on patient response

Each appointment lasts approximately 2 hours, as patients are monitored for safety after administration. Due to temporary side effects such as sedation or dizziness, patients must arrange transportation home and should not drive until the following day.

Esketamine depression treatment is available only through the FDA’s Risk Evaluation and Mitigation Strategy (REMS) program to ensure safe, clinic-certified administration.

The Potential Side Effects of Esketamine Treatment

Common side effects may include:

Dizziness
Nausea
Dissociation (a temporary feeling of being detached from surroundings)
Increased blood pressure
Headache
Fatigue or sedation

These effects are generally short-term and resolve the same day. Because Esketamine can temporarily affect alertness and blood pressure, monitoring during and after treatment is required.

Our mental health team carefully evaluates each patient to determine whether Esketamine is an appropriate and safe treatment option.

Why choose Mid Cities Psychiatry for Esketamine Treatments?

Choosing the right provider for interventional psychiatry treatments is essential. Mid Cities Psychiatry is committed to bring latest advancements for treatment-resistant mental health conditions. We combine science with compassionate care to provide the best possible treatment outcomes. Our board-certified team is experienced in providing advanced mental health treatments like Esketamine therapy, offering evidence-based mental health care and support. Here is how Mid Cities Psychiatry ensures to promote healing with expertise and comfort.

Comprehensive psychiatric evaluation before treatment
Accredited by the Joint Commission
Experienced medical professionals trained in esketamine administration
Continuous monitoring during every session
Integration with ongoing psychiatric care and medication management
A safe, calm, and supportive treatment environment

Our goal is not simply symptom relief — it is helping patients achieve meaningful, lasting improvement in mood, function, and overall quality of life.

We Accept All Major Insurance Plans

Set Free from Depression with Our Esketamine Therapy

Don’t let depression make your life miserable. Experience fewer depression symptoms and a more fulfilling life through our carefully guided esketamine therapy at Mid Cities Psychiatry. Contact Mid Cities Psychiatry today and learn more about how esketamine treatment helps you regain control of your mental health.

Esketamine Response Rate

FAQs About Esketamine Therapy

How quickly does Esketamine treatment work?

Some patients begin noticing improvement within the first few weeks of treatment, and in certain cases, symptom relief may occur sooner than with traditional antidepressants. However, response times vary. Esketamine therapy is used in combination with an oral antidepressant, and full therapeutic benefit may continue to develop over the course of treatment.

Will I feel “high” during treatment?

Esketamine for depression can cause temporary sensations such as dissociation, lightheadedness, or altered perception. Some patients describe feeling relaxed or detached. These effects are expected, monitored closely, and typically resolve within a few hours. Patients remain in the clinic under supervision until it is safe to leave.

Can I drive myself home after treatment?

No. Because ketamine nasal spray may cause sedation or temporary changes in alertness, patients must arrange transportation home after each session. Driving or operating heavy machinery is not permitted until the following day after a full night of rest.

How often do I need to receive Esketamine therapy?

Esketamine therapy begins with an induction phase of twice-weekly visits for four weeks. After that, the frequency typically decreases to once weekly or once every two weeks, depending on clinical response. Your provider will determine the most appropriate schedule based on symptom improvement and overall progress.

Is Esketamine covered by insurance?

Esketamine is FDA-approved for treatment-resistant depression and certain cases of major depressive disorder with suicidal thoughts. Many insurance plans provide coverage when medical necessity criteria are met.

Our team assists with benefits verification, prior authorization, and coordination of care to help patients understand their coverage before beginning esketamine treatments.

Is Spravato the same as ketamine?

Spravato contains esketamine, which is a refined, FDA-approved form of ketamine specifically developed for treatment-resistant depression. While both medications act on the brain’s glutamate system, they are not identical.

Spravato is administered as a nasal spray in a certified medical setting under the FDA’s REMS safety program and must be used in combination with an oral antidepressant. Traditional ketamine treatment is typically administered via intravenous (IV) infusion or intramuscular (IM) injection (also offered in our clinic) and is prescribed off-label for mood disorders.

Both treatments can be effective, but they differ in formulation, administration method, and regulatory requirements. Our mental health providers help determine which option may be most appropriate based on each patient’s clinical history and treatment goals.

What Our Patients Say

Real Stories, Real Recovery

I’ve been going to Dr. Kazi since 2015 and she has helped me get through a lot of my hardest times. When I came to her in 2015 my mind had taken over my body and my life. She got me through it. She is caring, professional and excellent at her God-given gift as a Psychiatrist. Thanks, Dr. Kazi for giving a part of yourself to many daily. You are a true Blessing to many.

I have been a patient for two years. Every staff member has been outstanding. Amanda Bell is a blessing. She is compassionate, and sincere, listens intently and is always able to calm me and help me focus and get the most from my treatments. Dr Kazi has been available whenever I need help. She is on top of my care and aggressively monitors my progress. I came to her suffering major depression and overall a mess. My mental health has substantially improved under her care and she is continuing to help me reach and maintain even higher levels of health. The office does have strict policies but everything is clear and patients are well informed at all times. The guidelines are appropriate and reasonable. I highly recommend this mental health clinic

Fantastic staff and providers, excellent services, amazing care, compassionate professionals, timely prescription refills, and a calm atmosphere. What more could you ask for?

I have had amazing experiences with this business, both on the medical and business side. Any issues I've experienced with billing have been handled gracefully and with patience; the staff are very easy to talk to and are understanding. I LOVE PA Hofer; she (and other staff) are always very quick to answer online Portal questions, are very flexible with visits, understand when it comes to medication costs/changes, and go the extra step when it comes to evidence-based practice.

I've been taking my mom to Dr. Kazi for the past 17 months and we still go. She is an amazing physician and her staff is very warm and welcoming. She has helped my mom when mom needed her the most. If it was not for Dr. Kazi's, I don't know what would have happened to my mom. I am so grateful to her. The bonus is her staff is awesome. Very response to emails and phone calls. Amanda is amazing!! I can't thank Dr. Kazi enough!!